Non-gonococcal Urethritis is an inflammation of the urethra caused by a bacterium other than gonorrhea. The most common cause of the inflammation is Chlamydia, but it is its own condition because other bacteria can cause the infection.

NGU can have sexual or non-sexual origins. It can be spread through vaginal, oral or anal sexual contact, but can also be caused by urinary tract infections, an inflamed prostate, or a tightening of the foreskin of the penis.

The best ways to prevent against NGU is to use latex condoms during all sexual encounters, keep numbers of sexual partners down, and wash the genital area after sex. People who are sexually active should also have regular checkups with a medical professional. Men between the ages of 15 and 30 with multiple sex partners are at highest risk for NGU. Women are less likely to have an inflamed urethra because of anatomical differences.

Symptoms of NGU usually surface one to five weeks after infection, and commonly include burning before or after urination, and unusual discharge. Often, the discharge is only noticed as a stain on the underwear of the infected person. The symptoms may only last a few days, but the infection may still be present. Medical treatment should be sought, as NGU can cause numerous complications if left untreated. In men, NGU can lead to infertility due to an inflammation of the testicles, arthritis and skin lesions. For women, the inflammation can lead to vaginal infections, Pelvic Inflammatory Disease, infertility, miscarriage, and dangerous pregnancies.